Isotretinoin

Isotretinoin is commonly sold under brand names such as Accutane, Roaccutane, and Amnesteem.
Isotretinoin is a powerful oral medication primarily used to treat severe acne that has not responded to other treatments. It is a retinoid, a derivative of vitamin A, that works by reducing the amount of oil released by the sebaceous glands in the skin, preventing clogged pores and promoting skin cell turnover. Isotretinoin is also effective in treating other skin conditions, such as rosacea and certain types of skin cancers. Due to its potency, isotretinoin is usually prescribed for a limited duration and under strict medical supervision.

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Isotrin

Capsule

20mg

Square Pharmaceuticals

Directions

  • Take isotretinoin exactly as prescribed by your healthcare provider, typically once or twice daily with food to enhance absorption.
  • Swallow the capsule whole; do not crush or chew it.
  • It may take several weeks to notice improvement in your acne; continue taking the medication as directed even if you do not see immediate results.
  • Do not share isotretinoin with others, as it is specifically prescribed for your condition.

Special Precautions

  • Inform your doctor if you have a history of liver disease, high cholesterol, or mental health issues before starting isotretinoin, as it may not be safe for these conditions.
  • Isotretinoin can cause serious birth defects; therefore, it is crucial to use effective birth control during treatment and for at least one month after stopping the medication if you are of childbearing potential.
  • Regular blood tests may be required to monitor liver function and lipid levels during treatment.
  • Avoid donating blood while taking isotretinoin and for at least one month after stopping, as it could harm a pregnant recipient.
  • Discuss any other medications or supplements you are taking with your healthcare provider, as isotretinoin can interact with certain drugs.

Side Effects

Common side effects of isotretinoin may include:

  • Dry skin and lips
  • Nosebleeds
  • Itching or rash
  • Muscle or joint pain
  • Fatigue

Serious side effects, though rare, may include severe headaches, vision changes, mood changes (including depression), and signs of allergic reactions. Seek immediate medical attention if you experience symptoms such as severe headache, vision disturbances, or signs of depression.

Missed Dosage

If you miss a dose of isotretinoin, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses to make up for the missed one.

Storage Requirements

  • Store isotretinoin at room temperature, between 68°F and 77°F (20°C to 25°C), away from moisture and direct sunlight.
  • Keep the medication in its original container, tightly closed when not in use.
  • Keep out of reach of children and pets.
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