Apremilast
Apremilast is commonly sold under the brand name Otezla.
Apremilast is an oral medication used to treat certain inflammatory conditions, including moderate to severe plaque psoriasis and psoriatic arthritis. It works by inhibiting an enzyme called phosphodiesterase 4 (PDE4), which helps reduce inflammation in the body. Apremilast helps decrease symptoms such as pain, swelling, and redness in people with psoriatic arthritis, and reduces the scaling and redness of the skin in those with psoriasis. Apremilast is generally prescribed when other treatments have not been effective or are not suitable.Tablets & Capsules
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Our Inventory
Image | Name | Type | Strength | Manufacturer | Contact Us |
 | Arsenor | Tablet | 10mg, 30mg | Beacon Pharmaceuticals |
Directions
- Take Apremilast exactly as prescribed by your healthcare provider, usually twice daily (once in the morning and once in the evening).
- Apremilast tablets should be swallowed whole with water, with or without food. Do not crush, chew, or split the tablets.
- Your doctor may start you on a low dose and gradually increase it over the first few days to reduce the risk of side effects.
- Continue taking Apremilast as directed, even if you start to feel better, unless advised otherwise by your healthcare provider.
Special Precautions
- Inform your doctor if you have a history of depression or other mood disorders, as Apremilast may cause or worsen mood changes, including depression and suicidal thoughts.
- Let your healthcare provider know if you have a history of kidney problems, as you may need a lower dose of Apremilast.
- Apremilast may cause weight loss in some individuals. If you experience significant or rapid weight loss, contact your healthcare provider.
- Apremilast can interact with certain medications, including enzyme inducers (like rifampin, carbamazepine, and phenobarbital). Make sure your healthcare provider is aware of all the medications and supplements you are taking.
- If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before starting Apremilast, as its safety in pregnancy and breastfeeding is not fully established.
Side Effects
Common side effects of Apremilast may include:
- Nausea
- Diarrhea
- Headache
- Upper respiratory tract infection
- Abdominal pain
Serious side effects are rare but may include mood changes (such as depression or thoughts of suicide), significant weight loss, or severe diarrhea. Contact your healthcare provider immediately if you experience any serious side effects.
Missed Dosage
If you miss a dose of Apremilast, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for a missed dose.
Storage Requirements
- Store Apremilast at room temperature, between 68°F and 77°F (20°C to 25°C), away from moisture and direct sunlight.
- Keep the medication in its original container, tightly sealed when not in use.
- Keep out of reach of children and pets.